Ethyl Acetate → Tert-butyl 3-[2-amino-3-cyano-6-(2-hydroxyphenyl)-4-pyridinyl]-1-piperidinecarboxylate
Reaction equation
[CH3:37][CH2:38][O:39][C:40](=[O:41])[CH3:42].[NH2:1][c:2]1[n:3][c:4](-[c:23]2[c:24]([O:29][CH2:30][c:31]3[cH:32][cH:33][cH:34][cH:35][cH:36]3)[cH:25][cH:26][cH:27][cH:28]2)[cH:5][c:6]([CH:10]2[CH2:11][N:12]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:13][CH2:14][CH2:15]2)[c:7]1[C:8]#[N:9]>>[NH2:1][c:2]1[n:3][c:4](-[c:23]2[c:24]([OH:29])[cH:25][cH:26][cH:27][cH:28]2)[cH:5][c:6]([CH:10]2[CH2:11][N:12]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:13][CH2:14][CH2:15]2)[c:7]1[C:8]#[N:9]Participants
3
Sources & evidence
- ORD record
- ord-649a1825cf8b420e954fb00e8eb6c3ab
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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