Potassium Cation → 2-Chloro-5-(cyclopentyloxy)pyrimidine

HRID 830915Notes

Reaction equation

HRID 830915 reaction equation
[C:15](=[O:16])([O-:17])[O-:18].[CH3:22][N:23]([CH3:24])[CH:25]=[O:26].[Cl:1][c:2]1[n:3][cH:4][c:5]([OH:8])[cH:6][n:7]1.[Cl:9][CH:10]1[CH2:11][CH2:12][CH2:13][CH2:14]1.[K+:19].[K+:20].[OH2:21]>>[Cl:1][c:2]1[n:3][cH:4][c:5]([O:8][CH:10]2[CH2:11][CH2:12][CH2:13][CH2:14]2)[cH:6][n:7]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 70252ChlorocyclopentaneHCID 145957002-Chloro-5-pyrimidinol

Product 1

HCID 574765592-Chloro-5-(cyclopentyloxy)pyrimidine

Sources & evidence

ORD record
ord-79ab4a494b2749fe8b306c8e6a856c5a
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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