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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 831228Generated: October 30, 2026

Chloroform → tert-Butyl 4-fluoro-4-(hydroxymethyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/831228

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroformHCID 6212—
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantAluminum CationHCID 104727—
ReactantHydrideHCID 166653—
ReactantEthyl N-Boc-4-fluoropiperidine-4-carboxylateHCID 21306965—
Producttert-Butyl 4-fluoro-4-(hydroxymethyl)piperidine-1-carboxylateHCID 22248400—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-7f36e96d169246089e2620d295418b2f
Source noteTest data from https://doi.org/10.1039/C8SC04228D