Dichloromethane → Trifluoroacetic acid

HRID 831385Notes

Reaction equation

HRID 831385 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([C:14](=[O:15])[c:16]2[s:17][cH:18][cH:19][n:20]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:28][CH2:29][Cl:30].[F:21][C:22]([C:23](=[O:24])[OH:25])([F:26])[F:27]>>[F:21][C:22]([C:23](=[O:24])[OH:25])([F:26])[F:27].[NH:8]1[CH2:9][CH2:10][N:11]([C:14](=[O:15])[c:16]2[s:17][cH:18][cH:19][n:20]2)[CH2:12][CH2:13]1

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 59625991(4-Boc-1-piperazinyl)(2-thiazolyl)methanone

Product 2

HCID 6422Trifluoroacetic acidHCID 21641598Piperazin-1-yl(thiazol-2-yl)methanone

Sources & evidence

ORD record
ord-058276fa7fa24e8fa98348d6f296d0fc
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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