Sodium ion → 2-(3-Bromo-5-chloro-phenyl)-malonic acid dimethyl ester

HRID 831454Notes

Reaction equation

HRID 831454 reaction equation
[Br:1][c:2]1[cH:3][c:4]([Br:9])[cH:5][c:6]([Cl:8])[cH:7]1.[C:10]([CH2:11][C:12](=[O:13])[O:14][CH3:15])(=[O:16])[O:17][CH3:18].[CH2:24]1[O:25][CH2:26][CH2:27][O:28][CH2:29]1.[Cl:21][CH2:22][Cl:23].[Cu:30][Br:31].[H-:19].[Na+:20]>>[c:2]1([CH:11]([C:10](=[O:16])[O:17][CH3:18])[C:12](=[O:13])[O:14][CH3:15])[cH:3][c:4]([Br:9])[cH:5][c:6]([Cl:8])[cH:7]1

Participants

8

Reactant 7

HCID 923Sodium ionHCID 6344DichloromethaneHCID 7943Dimethyl malonateHCID 24593copper(I) bromideHCID 312751,4-DioxaneHCID 846761,3-Dibromo-5-chlorobenzeneHCID 166653Hydride

Product 1

HCID 574588062-(3-Bromo-5-chloro-phenyl)-malonic acid dimethyl ester

Sources & evidence

ORD record
ord-3e4fae7679884a9590af2edd563c3bc5
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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