Bicarbonate Ion → tert-butyl 3-[4-({[(3-isopropyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)carbonyl]amino}methyl)piperidin-1-yl]propanoate

HRID 831650Notes

Reaction equation

HRID 831650 reaction equation
[C:24]([CH:25]=[CH2:26])(=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32].[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH:1]([CH3:2])([CH3:3])[n:4]1[c:5](=[O:23])[n:6]([C:13](=[O:14])[NH:15][CH2:16][CH:17]2[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]2)[c:7]2[c:8]1[cH:9][cH:10][cH:11][cH:12]2.[Na+:42].[O-:38][C:39]([OH:40])=[O:41]>>[CH:1]([CH3:2])([CH3:3])[n:4]1[c:5](=[O:23])[n:6]([C:13](=[O:14])[NH:15][CH2:16][CH:17]2[CH2:18][CH2:19][N:20]([CH2:26][CH2:25][C:24](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[CH2:21][CH2:22]2)[c:7]2[c:8]1[cH:9][cH:10][cH:11][cH:12]2

Participants

6

Reactant 5

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 8028TetrahydrofuranHCID 15458tert-Butyl acrylateHCID 442491883-isopropyl-2-oxo-N-(piperidin-4-ylmethyl)-2,3-dihydro-1H-benzimidazole-1-carboxamide

Product 1

HCID 68585760tert-butyl 3-[4-({[(3-isopropyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)carbonyl]amino}methyl)piperidin-1-yl]propanoate

Sources & evidence

ORD record
ord-6540b2cc0c614f3f93769fd911612a7f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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