Dichloromethane → N-[4-(1-Methyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6(5H)-ylcarbonyl)phenyl]-2-methylbenzamide

HRID 831686Notes

Reaction equation

HRID 831686 reaction equation
[CH3:16][c:17]1[c:18]([C:19](=[O:20])[NH:21][c:22]2[cH:23][cH:24][c:25]([C:26](=[O:27])[Cl:28])[cH:29][cH:30]2)[cH:31][cH:32][cH:33][cH:34]1.[CH3:1][c:2]1[n:3][n:4][c:5]2[n:6]1-[c:7]1[c:8]([cH:12][cH:13][cH:14][cH:15]1)[NH:9][CH2:10][CH2:11]2.[CH3:35][CH2:36][N:37]([CH2:38][CH3:39])[CH2:40][CH3:41].[Cl:42][CH2:43][Cl:44]>>[CH3:1][c:2]1[n:3][n:4][c:5]2[n:6]1-[c:7]1[c:8]([cH:12][cH:13][cH:14][cH:15]1)[N:9]([C:26]([c:25]1[cH:24][cH:23][c:22]([NH:21][C:19]([c:18]3[c:17]([CH3:16])[cH:34][cH:33][cH:32][cH:31]3)=[O:20])[cH:30][cH:29]1)=[O:27])[CH2:10][CH2:11]2

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 107074414-[(2-methylbenzoyl)amino]benzoyl ChlorideHCID 120995541-methyl-5,6-dihydro-4H-benzo[b][1,2,4]triazolo[4,3-d][1,4]diazepine

Product 1

HCID 54047942N-[4-(1-Methyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-6(5H)-ylcarbonyl)phenyl]-2-methylbenzamide

Sources & evidence

ORD record
ord-1305ec2d65cb4f27802ebf1778723e26
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…