Potassium Cation → MCH-1 antagonist 1
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[cH:5][n:6][n:7]([CH2:11][CH2:12][N:13]3[CH2:14][CH2:15][CH2:16][CH2:17]3)[c:8]2[cH:9][cH:10]1.[CH2:18]([c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1)[O:25][c:26]1[cH:27][c:28](=[O:32])[nH:29][cH:30][cH:31]1.[CH2:47]1[O:48][CH2:49][CH2:50][O:51][CH2:52]1.[Cl:53][CH2:54][Cl:55].[Cu:56][I:57].[K+:41].[K+:42].[NH2:33][CH:34]1[CH2:35][CH2:36][CH2:37][CH2:38][CH:39]1[NH2:40].[O-:43][C:44]([O-:45])=[O:46]>>[c:2]1(-[n:29]2[c:28](=[O:32])[cH:27][c:26]([O:25][CH2:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[cH:31][cH:30]2)[cH:3][c:4]2[cH:5][n:6][n:7]([CH2:11][CH2:12][N:13]3[CH2:14][CH2:15][CH2:16][CH2:17]3)[c:8]2[cH:9][cH:10]1Participants
9
Reactant 8
HCID 813Potassium Cation2×
HCID 46101,2-Diaminocyclohexane
HCID 6344Dichloromethane
HCID 19660Carbonate Ion
HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)
HCID 312751,4-Dioxane
HCID 36077244-Benzyloxy-2(1H)-pyridone
HCID 576255415-Bromo-1-(2-(pyrrolidin-1-yl)ethyl)-1H-indazoleProduct 1
Sources & evidence
- ORD record
- ord-974c24bf949940f5a52e8f7e07b52906
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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