Tetrahydrofuran → 3-[4-(2-chloro-5-fluoro-phenoxy)-piperidin-1-yl]-3-oxo-N-(5-phenyl-pyridin-2-yl)-propionamide
Reaction equation
[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[Cl:14][c:15]1[c:16]([O:17][CH:18]2[CH2:19][CH2:20][N:21]([C:24]([CH2:25][C:26](=[O:27])[OH:28])=[O:29])[CH2:22][CH2:23]2)[cH:30][c:31]([F:34])[cH:32][cH:33]1.[c:1]1(-[c:7]2[cH:8][cH:9][c:10]([NH2:13])[n:11][cH:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[cH:8][cH:9][c:10]([NH:13][C:26]([CH2:25][C:24]([N:21]3[CH2:20][CH2:19][CH:18]([O:17][c:16]4[c:15]([Cl:14])[cH:33][cH:32][c:31]([F:34])[cH:30]4)[CH2:23][CH2:22]3)=[O:29])=[O:27])[n:11][cH:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
4
Sources & evidence
- ORD record
- ord-bae6d716c7a449c18a7d8b06677220e1
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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