Dichloromethane → HCID 178432926, compound

HRID 831827Notes

Reaction equation

[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][cH:16][c:17](-[c:20]3[n:21][c:22]4[c:23]([n:24][cH:25][c:26]([Br:41])[c:27]4[N:28]4[CH2:29][CH2:30][N:31]([CH2:34][c:35]5[n:36][c:37]([CH3:40])[s:38][cH:39]5)[CH2:32][CH2:33]4)[nH:42]3)[cH:18][cH:19]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:50][CH2:51][Cl:52].[F:43][C:44]([F:45])([F:46])[C:47]([OH:48])=[O:49]>>[NH:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][cH:16][c:17](-[c:20]3[n:21][c:22]4[c:23]([n:24][cH:25][c:26]([Br:41])[c:27]4[N:28]4[CH2:29][CH2:30][N:31]([CH2:34][c:35]5[n:36][c:37]([CH3:40])[s:38][cH:39]5)[CH2:32][CH2:33]4)[nH:42]3)[cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 178432927tert-Butyl 4-(4-(6-bromo-7-(4-((2-methylthiazol-4-yl)methyl)piperazin-1-yl)-3H-imidazo[4,5-b]pyridin-2-yl)phenyl)piperazine-1-carboxylate

Product 1

HCID 178432926HCID 178432926, compound

Sources & evidence

ORD record: ord-2c2971b5e2b343fa9f51489bc9132bc3
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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