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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 831961Generated: October 30, 2026

Tetrahydrofuran → (+)-N-[5-Cycloheptyl-2,3-dihydro-1-methyl-2-oxo-1H-1,4-benzodiazepin-3-yl]N'[3-(N-methyl-N'-piperazinyl)phenyl]urea

https://huagongshe.com/reaction/831961

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantTriphosgeneHCID 94429—
Reactant3-(4-Methylpiperazin-1-yl)anilineHCID 11564613—
Reactant3-amino-5-cycloheptyl-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-oneHCID 21480464—
Product(+)-N-[5-Cycloheptyl-2,3-dihydro-1-methyl-2-oxo-1H-1,4-benzodiazepin-3-yl]N'[3-(N-methyl-N'-piperazinyl)phenyl]ureaHCID 15840131—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-88ed5fdf3e484fa6b02aff26497fd8de
Source noteTest data from https://doi.org/10.1039/C8SC04228D