Dichloromethane → 5-(4-tert-butylthiazol-2-ylamino)-N-(thiazol-2-yl)pyridine-2-sulfonamide
Reaction equation
[CH2:44]([Cl:45])[Cl:46].[CH3:8][O:9][c:10]1[cH:11][c:12]([O:38][CH3:39])[cH:40][cH:41][c:42]1[CH2:43][N:13]([S:14](=[O:15])(=[O:16])[c:17]1[n:18][cH:19][c:20]([NH:23][c:24]2[s:25][cH:26][c:27]([C:29]([CH3:30])([CH3:31])[CH3:32])[n:28]2)[cH:21][cH:22]1)[c:33]1[s:34][cH:35][cH:36][n:37]1.[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[NH:13]([S:14](=[O:15])(=[O:16])[c:17]1[n:18][cH:19][c:20]([NH:23][c:24]2[s:25][cH:26][c:27]([C:29]([CH3:30])([CH3:31])[CH3:32])[n:28]2)[cH:21][cH:22]1)[c:33]1[s:34][cH:35][cH:36][n:37]1Participants
4
Sources & evidence
- ORD record
- ord-76e858a3058e42a89ca4e5d5c831ced9
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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