Methanol → 2-[N-(5-Bromo-2-hydroxybenzyl)-N-ethylamino]pyridine-5-carboxylic Acid

HRID 832436Notes

Reaction equation

HRID 832436 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([OH:22])[c:6]([CH2:7][N:8]([CH2:9][CH3:10])[c:11]2[n:12][cH:13][c:14]([C:17](=[O:18])[O:19][CH3:20])[cH:15][cH:16]2)[cH:21]1.[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH3:30][OH:31].[Na+:24].[OH-:23]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([OH:22])[c:6]([CH2:7][N:8]([CH2:9][CH3:10])[c:11]2[n:12][cH:13][c:14]([C:17](=[O:18])[OH:19])[cH:15][cH:16]2)[cH:21]1

Participants

6

Reactant 5

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 8028TetrahydrofuranHCID 11728230methyl 2-[N-(2-hydroxy-5-bromobenzyl)-N-ethylamino]pyridine-5-carboxylate

Product 1

HCID 226225362-[N-(5-Bromo-2-hydroxybenzyl)-N-ethylamino]pyridine-5-carboxylic Acid

Sources & evidence

ORD record
ord-1e6307f821224c8c863cc9146c2ac342
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…