1,2-Dichloroethane → 1-cyclohexyl-3-[6-methyl-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-urea
Reaction equation
[CH3:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7][c:8]([NH2:10])[n:9]2)[n:11]1[CH2:12][O:13][CH2:14][CH2:15][Si:16]([CH3:17])([CH3:18])[CH3:19].[CH:20]1([N:26]=[C:27]=[O:28])[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]1.[Cl:29][CH2:30][CH2:31][Cl:32]>>[CH3:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7][c:8]([NH:10][C:27]([NH:26][CH:20]3[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]3)=[O:28])[n:9]2)[n:11]1[CH2:12][O:13][CH2:14][CH2:15][Si:16]([CH3:17])([CH3:18])[CH3:19]Participants
4
Sources & evidence
- ORD record
- ord-f3017b60abfa48f790d804d8955f53c8
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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