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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 832707Generated: October 29, 2026

Tetrahydrofuran → 4-((6-Chloroquinolin-2-yl)(5-ethoxy-2-fluoro-3-isopropoxyphenyl)methylamino)benzonitrile

https://huagongshe.com/reaction/832707

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant2-Bromo-6-chloroquinolineHCID 17933523—
Reactant(E)-4-(5-ethoxy-2-fluoro-3-isopropoxybenzylideneamino)benzonitrileHCID 57804014—
ReactantButyllithiumHCID 178418339—
Product4-((6-Chloroquinolin-2-yl)(5-ethoxy-2-fluoro-3-isopropoxyphenyl)methylamino)benzonitrileHCID 68816823—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-b1ae910bc8c841adabfabfe5a968559c
Source noteTest data from https://doi.org/10.1039/C8SC04228D