Tetrahydrofuran → 4-((6-Chloroquinolin-2-yl)(5-ethoxy-2-fluoro-3-isopropoxyphenyl)methylamino)benzonitrile

HRID 832707Notes

Reaction equation

[Br:1][c:2]1[n:3][c:4]2[cH:5][cH:6][c:7]([Cl:12])[cH:8][c:9]2[cH:10][cH:11]1.[CH2:18]([CH3:19])[O:20][c:21]1[cH:22][c:23]([O:38][CH:39]([CH3:40])[CH3:41])[c:24]([F:37])[c:25]([CH:26]=[N:27][c:28]2[cH:29][cH:30][c:31]([C:32]#[N:33])[cH:34][cH:35]2)[cH:36]1.[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:13][CH2:14][CH2:15][CH2:16][Li:17]>>[c:2]1([N:27]([CH2:26][c:25]2[c:24]([F:37])[c:23]([O:38][CH:39]([CH3:40])[CH3:41])[cH:22][c:21]([O:20][CH2:18][CH3:19])[cH:36]2)[c:28]2[cH:29][cH:30][c:31]([C:32]#[N:33])[cH:34][cH:35]2)[n:3][c:4]2[cH:5][cH:6][c:7]([Cl:12])[cH:8][c:9]2[cH:10][cH:11]1