Tetrahydrofuran → 2-Chloro-5-[4-(4-methyl-piperazin-1-yl)-benzoyl]-benzenesulfonamide

HRID 833002Notes

Reaction equation

HRID 833002 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([CH3:14])[CH2:12][CH2:13]2)[cH:6][cH:7]1.[C:15]([Li:16])([CH3:17])([CH3:18])[CH3:19].[Cl:20][c:21]1[c:22]([S:33]([NH2:34])(=[O:35])=[O:36])[cH:23][c:24]([C:25](=[O:26])[N:27]([O:28][CH3:29])[CH3:30])[cH:31][cH:32]1.[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1>>[c:2]1([C:25]([c:24]2[cH:23][c:22]([S:33]([NH2:34])(=[O:35])=[O:36])[c:21]([Cl:20])[cH:32][cH:31]2)=[O:26])[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([CH3:14])[CH2:12][CH2:13]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 118176751-(4-Bromophenyl)-4-methylpiperazineHCID 581073994-chloro-N-methoxy-N-methyl-3-sulfamoyl-benzamideHCID 178418306HCID 178418306, compound

Product 1

HCID 581074112-Chloro-5-[4-(4-methyl-piperazin-1-yl)-benzoyl]-benzenesulfonamide

Sources & evidence

ORD record
ord-a44a0f0c34b340b8a27e77a46086f8da
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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