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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 833053Generated: October 25, 2026

5-(2-Fluoro-4-(1-hydroxy-1-methylethyl)phenyl)-2-((6-formyl-2-pyridinyl)amino)-3-thiophenecarboxamide → 5-[2-Fluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-({6-[(2-oxo-3-oxa-1,8-diazaspiro[4.5]dec-8-yl)methyl]pyridin-2-yl}amino)thiophene-3-carboxamide

https://huagongshe.com/reaction/833053

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(2-Fluoro-4-(1-hydroxy-1-methylethyl)phenyl)-2-((6-formyl-2-pyridinyl)amino)-3-thiophenecarboxamideHCID 59526158—
Reactant8-[(6-Bromopyridin-2-yl)methyl]-3-oxa-1,8-diazaspiro[4.5]decan-2-oneHCID 86646263—
Product5-[2-Fluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-({6-[(2-oxo-3-oxa-1,8-diazaspiro[4.5]dec-8-yl)methyl]pyridin-2-yl}amino)thiophene-3-carboxamideHCID 59526006—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-8499857bebf34be8b4e2e9a1c191f8b3
Source noteTest data from https://doi.org/10.1039/C8SC04228D