Hydrochloric Acid → Ethyl 4-bromo-2-(trifluoromethyl)phenylcarbamate

HRID 833124Notes

Reaction equation

HRID 833124 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:9]([F:10])([F:11])[F:12])[c:5]([NH2:6])[cH:7][cH:8]1.[Cl:13][C:14](=[O:15])[O:16][CH2:17][CH3:18].[ClH:20].[OH2:19].[cH:21]1[cH:22][cH:23][n:24][cH:25][cH:26]1>>[Br:1][c:2]1[cH:3][c:4]([C:9]([F:10])([F:11])[F:12])[c:5]([NH:6][C:14](=[O:15])[O:16][CH2:17][CH3:18])[cH:7][cH:8]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 962WaterHCID 1049PyridineHCID 10928Ethyl chloroformateHCID 679604-Bromo-2-(trifluoromethyl)aniline

Product 1

HCID 22327384Ethyl 4-bromo-2-(trifluoromethyl)phenylcarbamate

Sources & evidence

ORD record
ord-eaafc86b54a44ea28207c54e9553202c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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