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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 833414Generated: October 26, 2026

Hydrochloric Acid → N-[[2-chloro-4-fluoro-3-(trifluoromethyl)phenyl]methyl]-1-methyl-5-oxopyrrolidine-2-carboxamide

https://huagongshe.com/reaction/833414

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantDichloromethaneHCID 6344—
Reactant2-Ethoxy-1-(ethoxycarbonyl)-1,2-dihydroquinolineHCID 27833—
Reactant1-methyl-5-oxo-DL-prolineHCID 13458634—
Reactant[2-Chloro-4-fluoro-3-(trifluoromethyl)phenyl]methanamineHCID 86617539—
ProductN-[[2-chloro-4-fluoro-3-(trifluoromethyl)phenyl]methyl]-1-methyl-5-oxopyrrolidine-2-carboxamideHCID 59303353—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-e11f9afd1c45401cafc7b7bc4843e597
Source noteTest data from https://doi.org/10.1039/C8SC04228D