Ethanol → Oxo-enzalutamide

HRID 833448Notes

Reaction equation

HRID 833448 reaction equation
[C:1](#[N:2])[c:3]1[c:4]([C:29]([F:30])([F:31])[F:32])[cH:5][c:6]([N:9]2[C:10](=[S:28])[N:11]([c:17]3[cH:18][c:19]([F:27])[c:20]([C:21](=[O:22])[NH:23][CH3:24])[cH:25][cH:26]3)[C:12]([CH3:15])([CH3:16])[C:13]2=[O:14])[cH:7][cH:8]1.[CH3:35][CH2:36][OH:37].[OH:33][OH:34]>>[C:1](#[N:2])[c:3]1[c:4]([C:29]([F:30])([F:31])[F:32])[cH:5][c:6]([N:9]2[C:10](=[O:33])[N:11]([c:17]3[cH:18][c:19]([F:27])[c:20]([C:21](=[O:22])[NH:23][CH3:24])[cH:25][cH:26]3)[C:12]([CH3:15])([CH3:16])[C:13]2=[O:14])[cH:7][cH:8]1

Participants

4

Reactant 3

HCID 702EthanolHCID 784Hydrogen PeroxideHCID 15951529Enzalutamide

Product 1

HCID 46898524Oxo-enzalutamide

Sources & evidence

ORD record
ord-046a1a2eef364dbe8d54cf8295fd6d7d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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