Phosphorus oxychloride → 7-(4-Chlorothieno[2,3-d]pyrimidin-5-yl)-2-phenylquinoline

HRID 833610Notes

Reaction equation

HRID 833610 reaction equation
[P:27]([Cl:28])([Cl:29])([Cl:30])=[O:31].[c:1]1(-[c:7]2[n:8][c:9]3[cH:10][c:11](-[c:17]4[cH:18][s:19][c:20]5[n:21][cH:22][nH:23][c:24](=[O:26])[c:25]45)[cH:12][cH:13][c:14]3[cH:15][cH:16]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[n:8][c:9]3[cH:10][c:11](-[c:17]4[cH:18][s:19][c:20]5[n:21][cH:22][n:23][c:24]([Cl:29])[c:25]45)[cH:12][cH:13][c:14]3[cH:15][cH:16]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 577623885-(2-phenylquinolin-7-yl)-3H-thieno[2,3-d]pyrimidin-4-one

Product 1

HCID 577623927-(4-Chlorothieno[2,3-d]pyrimidin-5-yl)-2-phenylquinoline

Sources & evidence

ORD record
ord-44ec6770c42249eca9a9415b051b05d6
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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