Pyridine → 1-Chloro-1-(4-methoxyphenyl)-1-trifluoromethylethane

HRID 833641Notes

Reaction equation

HRID 833641 reaction equation
[CH3:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1.[CH3:34][CH2:35][O:36][C:37]([CH3:38])=[O:39].[Cl:22][S:23](=[O:24])(=[O:25])[Cl:26].[F:1][C:2]([C:3]([CH3:4])([OH:5])[c:6]1[cH:7][cH:8][c:9]([O:12][CH3:13])[cH:10][cH:11]1)([F:14])[F:15].[cH:16]1[cH:17][cH:18][n:19][cH:20][cH:21]1>>[F:1][C:2]([C:3]([CH3:4])([c:6]1[cH:7][cH:8][c:9]([O:12][CH3:13])[cH:10][cH:11]1)[Cl:22])([F:14])[F:15]

Participants

6

Reactant 5

HCID 1049PyridineHCID 1140TolueneHCID 8857Ethyl AcetateHCID 24648Sulfuryl chlorideHCID 108677871,1,1-Trifluoro-2-(4-methoxyphenyl)propan-2-ol

Product 1

HCID 138856001-Chloro-1-(4-methoxyphenyl)-1-trifluoromethylethane

Sources & evidence

ORD record
ord-5771540ed777484b84f45d094ce5df4c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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