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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 833650Generated: October 30, 2026

Tetrahydrofuran → N-[3-(7-chloro-2-oxo-1,4-dihydro-2H-pyrimido[4,5-d]pyrimidin-3-yl)-4-methylphenyl]-3-trifluoromethylbenzamide

https://huagongshe.com/reaction/833650

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantTriphosgeneHCID 94429—
ReactantN-{3-[(2-chloro-4-methylaminopyrimidin-5-ylmethyl)amino]-4-methylphenyl}-3-trifluoromethylbenzamideHCID 86600918—
ProductN-[3-(7-chloro-2-oxo-1,4-dihydro-2H-pyrimido[4,5-d]pyrimidin-3-yl)-4-methylphenyl]-3-trifluoromethylbenzamideHCID 86600919—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-9897e4488e97498191e4b43f45930038
Source noteTest data from https://doi.org/10.1039/C8SC04228D