Methanol → tert-Butyl 3-{[(4-methoxyphenyl)methyl]amino}azetidine-1-carboxylate

HRID 833663Notes

Reaction equation

HRID 833663 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH:7]=[O:8])[cH:9][cH:10]1.[CH3:23][O:24][c:25]1[cH:26][cH:27][c:28]([CH2:29][NH:30][CH:31]2[CH2:32][CH2:33][CH2:34]2)[cH:35][cH:36]1.[CH3:37][OH:38].[NH2:11][CH:12]1[CH2:13][N:14]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:15]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][NH:11][CH:12]2[CH2:13][N:14]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:15]2)[cH:9][cH:10]1

Participants

5

Reactant 4

HCID 887MethanolHCID 312444-MethoxybenzaldehydeHCID 1516507Tert-butyl 3-aminoazetidine-1-carboxylateHCID 59313984N-[(4-methoxyphenyl)methyl]cyclobutanamine

Product 1

HCID 59313975tert-Butyl 3-{[(4-methoxyphenyl)methyl]amino}azetidine-1-carboxylate

Sources & evidence

ORD record
ord-f0972b4b0ad747928227edc970eab53e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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