O-Xylene → 2-(Trifluoromethyl)-1,4,5,6-tetrahydro-5-pyrimidinol
Reaction equation
[CH2:7]([O:8][C:10](=[O:9])[C:11]([F:12])([F:13])[F:14])[CH3:15].[NH2:1][CH2:2][CH:3]([CH2:4][NH2:5])[OH:6].[c:16]1([CH3:17])[c:18]([CH3:19])[cH:20][cH:21][cH:22][cH:23]1>>[NH:1]1[CH2:2][CH:3]([OH:6])[CH2:4][N:5]=[C:10]1[C:11]([F:12])([F:13])[F:14]Participants
4
Sources & evidence
- ORD record
- ord-56a5eeddcb154de6b34aefff1d2faaa6
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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