Sodium ion → Tert-butyl 4-(3-methoxy-4-(methoxycarbonyl)phenoxy)piperidine-1-carboxylate

HRID 833748Notes

Reaction equation

HRID 833748 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[cH:16][c:17]([OH:25])[c:18]([C:19](=[O:20])[O:21][CH3:22])[cH:23][cH:24]2)[CH2:12][CH2:13]1.[H-:29].[I:26][CH3:27].[Na+:28].[O:30]=[CH:31][N:32]([CH3:33])[CH3:34]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[cH:16][c:17]([O:25][CH3:27])[c:18]([C:19](=[O:20])[O:21][CH3:22])[cH:23][cH:24]2)[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 6328Methyl iodideHCID 166653HydrideHCID 105940774-(N-t-Butoxycarbonyl-4-piperidinyloxy)-2-hydroxybenzoic acid methyl ester

Product 1

HCID 10570851Tert-butyl 4-(3-methoxy-4-(methoxycarbonyl)phenoxy)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-098103fa503a468b94ce06a7171c72c4
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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