Dichloromethane → 4-(4-Aminomethylpiperidin-1-ylmethyl)-piperidine-1-carboxylic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3](=[O:4])[N:5]1[CH2:6][CH2:7][CH:8]([CH2:11][N:12]2[CH2:13][CH2:14][CH:15]([CH2:18][NH:19][C:20]([O:21][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:26])[CH2:16][CH2:17]2)[CH2:9][CH2:10]1.[Cl:34][CH2:35][Cl:36].[OH:27][C:28]([C:29]([F:30])([F:31])[F:32])=[O:33]>>[CH3:1][O:2][C:3](=[O:4])[N:5]1[CH2:6][CH2:7][CH:8]([CH2:11][N:12]2[CH2:13][CH2:14][CH:15]([CH2:18][NH2:19])[CH2:16][CH2:17]2)[CH2:9][CH2:10]1Participants
4
Sources & evidence
- ORD record
- ord-f41fcb5bc9c045afbb822767978c59c8
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…