Potassium Cation → trans-Dibenzyl-4-piperidino-cyclohexylamine

HRID 833950Notes

Reaction equation

HRID 833950 reaction equation
[Br:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][Br:29].[C:30](=[O:31])([O-:32])[O-:33].[K+:34].[K+:35].[NH2:1][CH:2]1[CH2:3][CH2:4][CH:5]([N:8]([CH2:9][c:10]2[cH:11][cH:12][cH:13][cH:14][cH:15]2)[CH2:16][c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[CH2:6][CH2:7]1.[O:37]=[CH:38][N:39]([CH3:40])[CH3:41].[OH2:36]>>[N:1]1([CH:2]2[CH2:3][CH2:4][CH:5]([N:8]([CH2:9][c:10]3[cH:11][cH:12][cH:13][cH:14][cH:15]3)[CH2:16][c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[CH2:6][CH2:7]2)[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 81001,5-DibromopentaneHCID 19660Carbonate IonHCID 20761835trans-1-Amino-4-dibenzylaminocyclohexane

Product 1

HCID 22562150trans-Dibenzyl-4-piperidino-cyclohexylamine

Sources & evidence

ORD record
ord-38f856e88dfa434c8867d2f9aac9d887
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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