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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 833998Generated: October 31, 2026

Tetrahydrofuran → 1-(4-[1-(Tert-butoxycarbonyl)-4-hydroxypiperidin-4-yl]phenyl}cyclopropanecarboxylic acid

https://huagongshe.com/reaction/833998

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantHexaneHCID 8058—
ReactantHeptaneHCID 8900—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
Reactant1-(4-Bromophenyl)cyclopropane-1-carboxylic acidHCID 16227966—
ReactantButyllithiumHCID 178418339—
ReactantHCID 178448196HCID 178448196—
Product1-(4-[1-(Tert-butoxycarbonyl)-4-hydroxypiperidin-4-yl]phenyl}cyclopropanecarboxylic acidHCID 66661592—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-d86dd3f37aa94d53844e17d0fb9c1c20
Source noteTest data from https://doi.org/10.1039/C8SC04228D