Tetrahydrofuran → 1-(4-[1-(Tert-butoxycarbonyl)-4-hydroxypiperidin-4-yl]phenyl}cyclopropanecarboxylic acid

HRID 833998Notes

Reaction equation

[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([C:11](=[O:12])[OH:13])[CH2:9][CH2:10]2)[cH:6][cH:7]1.[CH2:14]([Mg:15][CH2:16][CH2:17][CH2:18][CH3:19])[CH2:20][CH2:21][CH3:22].[CH2:23]([Li:24])[CH2:25][CH2:26][CH3:27].[CH2:55]1[O:56][CH2:57][CH2:58][CH2:59]1.[CH3:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH3:48].[CH3:49][CH2:50][CH2:51][CH2:52][CH2:53][CH3:54].[O:28]=[C:29]1[CH2:30][CH2:31][N:32]([C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[CH2:33][CH2:34]1>>[c:2]1([C:29]2([OH:28])[CH2:30][CH2:31][N:32]([C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[CH2:33][CH2:34]2)[cH:3][cH:4][c:5]([C:8]2([C:11](=[O:12])[OH:13])[CH2:9][CH2:10]2)[cH:6][cH:7]1