Benzyl Bromide → 1-Benzyl-6-chloro-2-oxo-4-[4-(thiophene-2-carbonyl)-piperazin 1-yl]-1,2-dihydro-[1,8]-naphthyridine-3-carbonitrile
Reaction equation
[Br:28][CH2:29][c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1.[Cl:1][c:2]1[cH:3][c:4]2[c:5]([N:15]3[CH2:16][CH2:17][N:18]([C:21](=[O:22])[c:23]4[s:24][cH:25][cH:26][cH:27]4)[CH2:19][CH2:20]3)[c:6]([C:13]#[N:14])[c:7](=[O:12])[nH:8][c:9]2[n:10][cH:11]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([N:15]3[CH2:16][CH2:17][N:18]([C:21](=[O:22])[c:23]4[s:24][cH:25][cH:26][cH:27]4)[CH2:19][CH2:20]3)[c:6]([C:13]#[N:14])[c:7](=[O:12])[n:8]([CH2:29][c:30]3[cH:31][cH:32][cH:33][cH:34][cH:35]3)[c:9]2[n:10][cH:11]1Participants
3
Sources & evidence
- ORD record
- ord-95c3cd2ac6a4453d9f315372847430c9
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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