Methanol → 1-(4-Fluorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one
Reaction equation
[BH4-:18].[CH2:20]1[O:21][CH2:22][CH2:23][CH2:24]1.[CH3:25][OH:26].[F:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH:10]([C:14](=[O:15])[O:16][CH3:17])[CH2:11][C:12]2=[O:13])[cH:6][cH:7]1.[Na+:19]>>[F:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH:10]([CH2:14][OH:15])[CH2:11][C:12]2=[O:13])[cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-bbe8331dcdf84d9f98a1f85afdabed23
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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