Toluene → 5-Fluoro-N-(2-fluoro-4-(morpholinomethyl)phenyl)-4-(2-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl)pyrimidin-2-amine

HRID 834491Notes

Reaction equation

[Br:21][c:22]1[c:23]([F:35])[cH:24][c:25]([CH2:26][N:27]2[CH2:28][CH2:29][O:30][CH2:31][CH2:32]2)[cH:33][cH:34]1.[CH3:36][C:37]1([CH3:38])[c:39]2[cH:40][cH:41][cH:42][c:43]([P:44]([c:45]3[cH:46][cH:47][cH:48][cH:49][cH:50]3)[c:51]3[cH:52][cH:53][cH:54][cH:55][cH:56]3)[c:57]2[O:58][c:59]2[c:60]1[cH:61][cH:62][cH:63][c:64]2[P:65]([c:66]1[cH:67][cH:68][cH:69][cH:70][cH:71]1)[c:72]1[cH:73][cH:74][cH:75][cH:76][cH:77]1.[CH3:78][c:79]1[cH:80][cH:81][cH:82][cH:83][cH:84]1.[F:1][c:2]1[c:3](-[c:9]2[cH:10][n:11][c:12]([CH3:20])[n:13]2[CH:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[n:4][c:5]([NH2:8])[n:6][cH:7]1>>[F:1][c:2]1[c:3](-[c:9]2[cH:10][n:11][c:12]([CH3:20])[n:13]2[CH:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[n:4][c:5]([NH:8][c:22]2[c:23]([F:35])[cH:24][c:25]([CH2:26][N:27]3[CH2:28][CH2:29][O:30][CH2:31][CH2:32]3)[cH:33][cH:34]2)[n:6][cH:7]1