Indole-3-Carboxylic Acid → 5-Bromo-1'-(1H-indol-3-ylcarbonyl)spiro[indole-3,4'-piperidin]-2(1H)-one
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[NH:7][C:6](=[O:11])[C:5]21[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]1.[OH:17][C:18](=[O:19])[c:20]1[cH:21][nH:22][c:23]2[cH:24][cH:25][cH:26][cH:27][c:28]12>>[Br:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[NH:7][C:6](=[O:11])[C:5]21[CH2:12][CH2:13][N:14]([C:18](=[O:17])[c:20]2[cH:21][nH:22][c:23]3[cH:24][cH:25][cH:26][cH:27][c:28]23)[CH2:15][CH2:16]1Participants
3
Sources & evidence
- ORD record
- ord-210cc8888c7447ea83445ce8e598d3fd
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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