Dichloromethane → 3-(Thiophen-2-yl)pyrrolidine

HRID 834600Notes

Reaction equation

[Cl:18][CH2:19][Cl:20].[F:21][C:22]([F:23])([F:24])[C:25]([OH:26])=[O:27].[s:1]1[c:2]([CH:6]2[CH2:7][N:8]([C:11]([O:12][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:17])[CH2:9][CH2:10]2)[cH:3][cH:4][cH:5]1>>[s:1]1[c:2]([CH:6]2[CH2:7][NH:8][CH2:9][CH2:10]2)[cH:3][cH:4][cH:5]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 68728651tert-Butyl 3-(thiophen-2-yl)pyrrolidine-1-carboxylate

Product 1

HCID 150299073-(Thiophen-2-yl)pyrrolidine

Sources & evidence

ORD record: ord-fefe8cae32894de8a0efd6545aff2baa
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…