Acetonitrile → Tert-butyl 4-(2-bromobenzyl)piperazine-1-carboxylate

HRID 834605Notes

Reaction equation

HRID 834605 reaction equation
[Br:23][c:24]1[c:25]([CH2:26][Br:27])[cH:28][cH:29][cH:30][cH:31]1.[CH3:32][C:33]#[N:34].[CH:14]([N:15]([CH:16]([CH3:17])[CH3:18])[CH2:19][CH3:20])([CH3:21])[CH3:22].[N:1]1([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1>>[N:1]1([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:2][CH2:3][N:4]([CH2:26][c:25]2[c:24]([Br:23])[cH:31][cH:30][cH:29][cH:28]2)[CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 6342AcetonitrileHCID 769652-Bromobenzyl bromideHCID 81531DiisopropylethylamineHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 20754660Tert-butyl 4-(2-bromobenzyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-7e3e9b5ef31944d987fd4a400d204ec5
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…