Dichloromethane → 3-(2-Cyclopropylmethoxyethylidene)-8-aza-bicyclo[3.2.1]octane

HRID 834609Notes

Reaction equation

HRID 834609 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH:9]2[CH2:10][C:11](=[CH:16][CH2:17][O:18][CH2:19][CH:20]3[CH2:21][CH2:22]3)[CH2:12][CH:13]1[CH2:14][CH2:15]2)([CH3:5])([CH3:6])[CH3:7].[Cl:30][CH2:31][Cl:32].[F:23][C:24]([F:25])([F:26])[C:27]([OH:28])=[O:29]>>[NH:8]1[CH:9]2[CH2:10][C:11](=[CH:16][CH2:17][O:18][CH2:19][CH:20]3[CH2:21][CH2:22]3)[CH2:12][CH:13]1[CH2:14][CH2:15]2

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 689113073-(2-Cyclopropylmethoxyethylidene)-8-azabicyclo[3.2.1]octane-8-carboxylic acid t-butyl ester

Product 1

HCID 689104243-(2-Cyclopropylmethoxyethylidene)-8-aza-bicyclo[3.2.1]octane

Sources & evidence

ORD record
ord-1927d5dd66ff456eb04ba675a73a6d07
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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