Dimethylformamide → 4-Chloro-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinazoline
Reaction equation
[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([CH2:8][CH2:9][CH2:10][O:11][c:12]2[c:13]([O:23][CH3:24])[cH:14][c:15]3[c:16](=[O:22])[nH:17][cH:18][n:19][c:20]3[cH:21]2)[CH2:6][CH2:7]1.[O:25]=[CH:26][N:27]([CH3:28])[CH3:29].[S:30]([Cl:31])([Cl:32])=[O:33]>>[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([CH2:8][CH2:9][CH2:10][O:11][c:12]2[c:13]([O:23][CH3:24])[cH:14][c:15]3[c:16]([Cl:32])[n:17][cH:18][n:19][c:20]3[cH:21]2)[CH2:6][CH2:7]1Participants
4
Sources & evidence
- ORD record
- ord-78bc15a4d6a84f6b9850abcf148ed8a3
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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