HCID 86680359, compound → (R)-3-Methyl-2-oxoimidazolidine-4-carboxylic Acid tert-butyl Ester

Participants

Reaction Steps

To a solution of (R)-3-methyl-2-oxoimidazolidine-1,4-dicarboxylic acid 1-benzyl ester 4-tert-butyl ester (167 mg) in methanol (1.7 ml) was added 10 wt % palladium on carbon at room temperature, and the mixture was stirred for 15 hours under one atom. of hydrogen. Under nitrogen atmosphere, this reaction solution was filtered through Celite, and eluted with methanol. The filtrate was concentrated under reduced pressure to give the titled compound (94 mg).

Provenance & Evidence