Acetate → 1-(2-(4-(6-Methoxy-2-(thiophen-2-yl)naphthalen-1-yloxy)phenoxy)ethyl)piperidine
Reaction equation
[CH3:75][C:76]#[N:77].[CH:45]1([P:46]([CH:47]2[CH2:48][CH2:49][CH2:50][CH2:51][CH2:52]2)[CH:53]2[CH2:54][CH2:55][CH2:56][CH2:57][CH2:58]2)[CH2:59][CH2:60][CH2:61][CH2:62][CH2:63]1.[Cs+:65].[F-:64].[F:1][C:2]([F:3])([F:4])[S:5]([O:6][c:7]1[c:8]([O:19][c:20]2[cH:21][cH:22][c:23]([O:26][CH2:27][CH2:28][N:29]3[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34]3)[cH:24][cH:25]2)[c:9]2[cH:10][cH:11][c:12]([O:17][CH3:18])[cH:13][c:14]2[cH:15][cH:16]1)(=[O:35])=[O:36].[O-:67][C:68]([CH3:69])=[O:70].[O-:71][C:72]([CH3:73])=[O:74].[Pd+2:66].[s:37]1[c:38]([B:42]([OH:43])[OH:44])[cH:39][cH:40][cH:41]1>>[c:7]1(-[c:38]2[s:37][cH:41][cH:40][cH:39]2)[c:8]([O:19][c:20]2[cH:21][cH:22][c:23]([O:26][CH2:27][CH2:28][N:29]3[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34]3)[cH:24][cH:25]2)[c:9]2[cH:10][cH:11][c:12]([O:17][CH3:18])[cH:13][c:14]2[cH:15][cH:16]1Participants
9
Reactant 8
HCID 175Acetate2×
HCID 6342Acetonitrile
HCID 28179Fluoride Ion
HCID 75806Tricyclohexylphosphine
HCID 104967Cesium cation
HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)
HCID 27339602-Thiopheneboronic acid
HCID 116133766-Methoxy-1-(4-(2-(piperidin-1-yl)ethoxy)phenoxy)naphthalen-2-yl trifluoromethanesulfonateProduct 1
Sources & evidence
- ORD record
- ord-8f487bec16d842809935b3c50687eced
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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