Dichloromethane → Trifluoroacetic acid

HRID 835314Notes

Reaction equation

HRID 835314 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH:10]([O:12][c:13]2[cH:14][n:15][c:16]([Br:19])[cH:17][cH:18]2)[CH2:11]1)([CH3:5])([CH3:6])[CH3:7].[Cl:27][CH2:28][Cl:29].[F:20][C:21]([C:22](=[O:23])[OH:24])([F:25])[F:26]>>[F:20][C:21]([C:22](=[O:23])[OH:24])([F:25])[F:26].[NH:8]1[CH2:9][CH:10]([O:12][c:13]2[cH:14][n:15][c:16]([Br:19])[cH:17][cH:18]2)[CH2:11]1

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 594737911-Boc-3-((6-bromopyridin-3-YL)oxy)azetidine

Product 2

HCID 6422Trifluoroacetic acidHCID 594737945-(Azetidin-3-yloxy)-2-bromopyridine

Sources & evidence

ORD record
ord-758fb73486904da79dd0704754465f37
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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