Trifluoroacetic acid → 5-[(cis-4-[4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]cyclohexylmethyl)thio]-4H-1,2,4-triazol-3-amine

HRID 835319Notes

Reaction equation

HRID 835319 reaction equation
[CH3:1][Si:2]([CH3:3])([CH3:4])[CH2:5][CH2:6][O:35][CH2:36][n:7]1[cH:8][cH:9][c:10]2[c:11]1[n:12][cH:13][n:14][c:15]2-[c:16]1[cH:17][n:18][n:19]([CH:21]2[CH2:22][CH2:23][CH:24]([CH2:27][S:28][c:29]3[nH:30][c:31]([NH2:34])[n:32][n:33]3)[CH2:25][CH2:26]2)[cH:20]1.[F:37][C:38]([F:39])([F:40])[C:41]([OH:42])=[O:43]>>[nH:7]1[cH:8][cH:9][c:10]2[c:11]1[n:12][cH:13][n:14][c:15]2-[c:16]1[cH:17][n:18][n:19]([CH:21]2[CH2:22][CH2:23][CH:24]([CH2:27][S:28][c:29]3[nH:30][c:31]([NH2:34])[n:32][n:33]3)[CH2:25][CH2:26]2)[cH:20]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 178504210HCID 178504210, compound

Product 1

HCID 1785092015-[(cis-4-[4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]cyclohexylmethyl)thio]-4H-1,2,4-triazol-3-amine

Sources & evidence

ORD record
ord-2960f6364de147a38acab48cf966da15
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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