Dimethylformamide → 4-CHLORO-6-FLUOROPYRIDO[3,4-D]PYRIMIDINE

HRID 835356Notes

Reaction equation

[F:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7][nH:8][c:9]2=[O:10])[cH:11][n:12]1.[O:13]=[CH:14][N:15]([CH3:16])[CH3:17].[S:18]([Cl:19])([Cl:20])=[O:21]>>[F:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7][n:8][c:9]2[Cl:20])[cH:11][n:12]1

Participants

Reactant 3

HCID 6228Dimethylformamide

HCID 24386Thionyl Chloride

HCID 1354173706-fluoropyrido[3,4-d]pyrimidin-4-ol

Product 1

HCID 106790414-CHLORO-6-FLUOROPYRIDO[3,4-D]PYRIMIDINE

Sources & evidence

ORD record: ord-99b46c5637c0415bb17e1388a38676f8
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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