Dimethyl Sulfoxide → Sorafenib

HRID 835429Notes

Reaction equation

[CH3:45][S:46](=[O:47])[CH3:48].[CH3:49][C:50]#[N:51].[Cl:1][c:2]1[c:3]([C:12]([F:13])([F:14])[F:15])[cH:4][c:5]([NH:8][C:9](=[O:10])[NH2:11])[cH:6][cH:7]1.[N:16]12[CH2:17][CH2:18][CH2:19][N:20]=[C:21]1[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26]2.[NH2:27][c:28]1[cH:29][cH:30][c:31]([O:32][c:33]2[cH:34][c:35]([C:39](=[O:40])[NH:41][CH3:42])[n:36][cH:37][cH:38]2)[cH:43][cH:44]1>>[Cl:1][c:2]1[c:3]([C:12]([F:13])([F:14])[F:15])[cH:4][c:5]([NH:8][C:9](=[O:10])[NH:11][c:28]2[cH:29][cH:30][c:31]([O:32][c:33]3[cH:34][c:35]([C:39](=[O:40])[NH:41][CH3:42])[n:36][cH:37][cH:38]3)[cH:43][cH:44]2)[cH:6][cH:7]1