Tetrahydrofuran → 1-[5-Chloro-2-(trifluoromethyl)benzyl]-7-(1H-pyrrol-3-yl)-1,2,3,4-tetrahydro-pyrido[2,3-b]pyrazine

HRID 835488Notes

Reaction equation

[CH3:2][CH2:3][CH2:4][CH2:5][N+:6]([CH2:7][CH2:8][CH2:9][CH3:10])([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:15][CH2:16][CH2:17][CH3:18].[Cl:19][c:20]1[cH:21][cH:22][c:23]([C:52]([F:53])([F:54])[F:55])[c:24]([CH2:25][N:26]2[c:27]3[c:28]([n:32][cH:33][c:34](-[c:36]4[cH:37][n:38]([Si:41]([CH:42]([CH3:43])[CH3:44])([CH:45]([CH3:46])[CH3:47])[CH:48]([CH3:49])[CH3:50])[cH:39][cH:40]4)[cH:35]3)[NH:29][CH2:30][CH2:31]2)[cH:51]1.[F-:1].[O:56]1[CH2:57][CH2:58][CH2:59][CH2:60]1>>[Cl:19][c:20]1[cH:21][cH:22][c:23]([C:52]([F:53])([F:54])[F:55])[c:24]([CH2:25][N:26]2[c:27]3[c:28]([n:32][cH:33][c:34](-[c:36]4[cH:37][nH:38][cH:39][cH:40]4)[cH:35]3)[NH:29][CH2:30][CH2:31]2)[cH:51]1