p-Toluenesulfonic acid → 2-(4'-Bromo-3',5'-difluorophenyl)-5-pentyl-1,3-dioxane

HRID 835514Notes

Reaction equation

HRID 835514 reaction equation
[Br:11][c:12]1[c:13]([F:21])[cH:14][c:15]([CH:16]=[O:17])[cH:18][c:19]1[F:20].[CH2:1]([CH2:2][CH2:3][CH2:4][CH3:5])[CH:6]([CH2:7][OH:8])[CH2:9][OH:10].[CH3:22][c:23]1[cH:24][cH:25][c:26]([S:27]([OH:28])(=[O:29])=[O:30])[cH:31][cH:32]1.[Cl:33][CH2:34][Cl:35]>>[CH2:1]([CH2:2][CH2:3][CH2:4][CH3:5])[CH:6]1[CH2:7][O:8][CH:16]([c:15]2[cH:14][c:13]([F:21])[c:12]([Br:11])[c:19]([F:20])[cH:18]2)[O:10][CH2:9]1

Participants

5

Reactant 4

HCID 6101p-Toluenesulfonic acidHCID 6344DichloromethaneHCID 1175092-Pentyl-1,3-propanediolHCID 234437854-Bromo-3,5-difluorobenzaldehyde

Product 1

HCID 189615282-(4'-Bromo-3',5'-difluorophenyl)-5-pentyl-1,3-dioxane

Sources & evidence

ORD record
ord-8a6a1a5bc5ad4d35bda69c0a18c45e37
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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