Dichloromethane → 2-Amino-1-[4-cyclopentyl-6-(6-fluoro-1H-indol-3-yl)-hexahydro-pyrrolo[3,2-b]pyrrol-1-yl]-3,3-dimethyl-butan-1-one
Reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH:8]([C:9]([CH3:10])([CH3:11])[CH3:12])[C:13](=[O:14])[N:15]1[CH:16]2[CH:17]([CH2:18][CH2:19]1)[N:20]([CH:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1)[CH2:21][CH:22]2[c:23]1[cH:24][nH:25][c:26]2[cH:27][c:28]([F:32])[cH:29][cH:30][c:31]12)([CH3:5])([CH3:6])[CH3:38].[Cl:46][CH2:47][Cl:48].[F:39][C:40]([F:41])([F:42])[C:43]([OH:44])=[O:45]>>[NH2:7][CH:8]([C:9]([CH3:10])([CH3:11])[CH3:12])[C:13](=[O:14])[N:15]1[CH:16]2[CH:17]([CH2:18][CH2:19]1)[N:20]([CH:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1)[CH2:21][CH:22]2[c:23]1[cH:24][nH:25][c:26]2[cH:27][c:28]([F:32])[cH:29][cH:30][c:31]12Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-0196f769d2be43f5a8a82c9a72f92dd0
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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