Dichloromethane → Trifluoroacetic acid

HRID 835825Notes

Reaction equation

HRID 835825 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH2:8][CH:9]1[CH2:10][N:11]([c:15]2[cH:16][c:17]3[c:21]([c:22]([F:24])[cH:23]2)[N:20]([CH2:25][CH2:26][CH3:27])[C:19](=[O:28])[CH2:18]3)[C:12](=[O:14])[O:13]1)([CH3:5])([CH3:6])[CH3:29].[Cl:37][CH2:38][Cl:39].[F:30][C:31]([C:32](=[O:33])[OH:34])([F:35])[F:36]>>[F:30][C:31]([C:32](=[O:33])[OH:34])([F:35])[F:36].[NH2:7][CH2:8][CH:9]1[CH2:10][N:11]([c:15]2[cH:16][c:17]3[c:21]([c:22]([F:24])[cH:23]2)[N:20]([CH2:25][CH2:26][CH3:27])[C:19](=[O:28])[CH2:18]3)[C:12](=[O:14])[O:13]1

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 69274123tert-butyl N-[[3-(7-fluoro-2-oxo-1-propyl-3H-indol-5-yl)-2-oxo-1,3-oxazolidin-5-yl]methyl]carbamate

Product 2

HCID 6422Trifluoroacetic acidHCID 692764875-(aminomethyl)-3-(7-fluoro-2-oxo-1-propyl-3H-indol-5-yl)-1,3-oxazolidin-2-one

Sources & evidence

ORD record
ord-319393aeaf1e4e0e8ecb07c6adc63cf1
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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