Trifluoroacetic acid → 2-(benzylamino)-5-(3-fluoro-4-hydroxyphenyl)-3-methylpyrimidin-4(3H)-one
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][c:9]1[n:10][cH:11][c:12](-[c:17]2[cH:18][c:19]([F:31])[c:20]([O:23][CH2:24][c:25]3[cH:26][cH:27][cH:28][cH:29][cH:30]3)[cH:21][cH:22]2)[c:13](=[O:16])[n:14]1[CH3:15].[F:32][C:33]([F:34])([F:35])[C:36]([OH:37])=[O:38]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][c:9]1[n:10][cH:11][c:12](-[c:17]2[cH:18][c:19]([F:31])[c:20]([OH:23])[cH:21][cH:22]2)[c:13](=[O:16])[n:14]1[CH3:15]Participants
3
Sources & evidence
- ORD record
- ord-df93f96d68964efbb7d336be8d0f2c2a
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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